5 Simple Statements About Diclofenac Sodium Explained
Gastrointestinal (GI): NSAIDs that block COX-1 action have correlations with GI difficulties due to inhibition with the synthesis of gastroprotective agents for instance PGE2 and also other prostaglandins. This inhibition brings about reduced mucin creation by gastric epithelial cells, less bicarbonate secretion, and less epithelial cell turnover,